Insect antifeeding limonoids from the chinaberry tree melia azedarach linn and related compounds; polygodial and warburganal, antifungal sesquiterpene dialdehydes and their synergies; marine bromoperoxidases-chemoenzymatic applications; LC-hyphenated techniques in the search for new bioactive plant constituents; determination of the absolute configuration of biologically active compounds by the modified Mosher's method; circular dichroism spectroscopy and the absolute stereochemistry of biologically active compounds; recent applications of circular dichronism to carbohydrate conformational analysis and direct determination of drug levels; furan-terminated cationic pi-cyclization in the synthesis of natural products; chemistry and biology of semisynthetic avermectins; chemical and biological approaches to molecular diversity - applications to drug discovery; imidazoline receptors and their endogenous ligands; oxidoredox suppression of fungal infections by novel pharmacophores; a mechanistic analysis of C-O bond cleavage events with a comparison to 3,6-dideoxysugar formation; the molecular mechanism of amyloidosis in Alzheimer's disease; bacteriorhodospin structure/function studies -use of the dimethyl retinal analogs for probing of the Arg82Ala mutant; autonomous genomes; stereo-chemical considerations of immunoglobulin heavy chain enhancer activation.
PDF格式,491页。生物化学界面。